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1·Lawlessness is a major problem.

违反法律是一个严重的问题。《柯林斯英汉双解大词典》

2·Stress is a major problem of modern life.

压力是现代生活中的主要问题。《牛津词典》

3·One major problem did present itself, though.

不过，确实出现了一个重大问题。《牛津词典》

4·It would appear that this was a major problem.

看来这是个主要问题。《牛津词典》

5·Drug abuse has long been a major problem for the authorities there.

毒品滥用长期以来一直是那里的当局的一大难题。《柯林斯英汉双解大词典》

6·Shopping becomes a major problem, and for anything slightly out of the ordinary you have to go on an expedition to the nearest large town.

购物成了大问题，要想买到任何一种稍不寻常的东西，你就得赶远路到最近的市镇。

7·So this is a major problem.

所以，这是一个大问题。

8·So, it is a problem, major problem.

因此说，这是个问题，是个主要问题。

9·The first major problem is staffing.

第一个主要问题是员工。

10·This is a major problem in the UK.

这就是英国的症结之一。