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1·Chronic allograft nephropathy (CAN) is the main cause of renal allograft failure after transplantation.

慢性移植肾肾病(CAN)是移植肾失功的主要原因。

2·Chronic allograft nephropathy (CAN) is the main cause resulting in failure of renal transplantation, whose pathogenesis is not clear at present.

慢性移植性肾病是导致肾移植失败的主要原因，其发病机制目前尚不清楚。

3·Conclusion the up-regulated expression of MCP-1 and RANTES in transplant kidney tissue may play a role in the pathogenesis of chronic allograft nephropathy.

结论肾组织中MCP 1和RANTES的表达升高可能与慢性移植肾肾病的发生有关。

4·Objective To investigate the expression of monocyte chemoattractant protein 1 (MCP-1) and RANTES and their significance in the pathogenesis of chronic allograft nephropathy.

目的探讨慢性移植肾肾病大鼠模型肾组织中单核细胞趋化因子1（MCP 1）和RANTES的表达及意义。

5·Objective To study the expression and role of matrix metalloproteinase-9 (MMP-9) in the early stage after renal transplantation by using standard rat model of chronic allograft nephropathy (CAN).

目的探讨基质金属蛋白酶- 9 (MMP - 9)在大鼠慢性同种移植肾病(CAN)早期发病中的表达。