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1·PS 341 is a potent and selective inhibitor of the proteasome.

PS 341是蛋白酶体有效的选择性抑制药。

2·EIN3 is regulated by a proteasome-mediated protein degradation pathway.

EIN3受到蛋白酶体介导的蛋白降解途径的调节。

3·Bortezonib (velcade) is the first proteasome inhibitor that has entered clinical trial.

波替单抗(万珂)是第一个进入临床试验的蛋白酶体抑制剂。

4·Proteasome inhibitors can selectively promote the apoptosis of tumor cells and overcome MDR.

蛋白酶体抑制剂可选择性地促进肿瘤细胞凋亡，逆转多药耐药。

5·Pharmacodynamic assay has shown that inhibition of proteasome is dose dependent and reversible.

药效学分析表明蛋白酶体抑制药的抑制作用有剂量依赖性和可逆性。

6·Components in charge of this process include ubiquitin, its startup enzymes, and proteasome system.

负责执行这个调控过程的组成成分包括泛素及其启动酶系统和蛋白酶体系统。

7·Inhibition of proteasome has been emerging as a promising approach in pathway-directed cancer therapy.

蛋白酶体的抑制在肿瘤的信号通路定向治疗方面已经成为一个极其有希望的途径。

8·Objective To determine the influence of ubiquitin-proteasome in regulating the TRAIL-mediated apoptosis.

目的：探讨泛肽蛋白酶体对TRAIL诱导细胞凋亡作用的影响。

9·Ubiquitin is a conserved polypeptide unit that plays an important role in the ubiquitin-proteasome pathway.

泛素是一种保守的多肽单元，在泛素蛋白酶体途径中起重要作用。

10·Objective To isolate and purify 20S proteasome from normal rat spleen and observe its morphologic features.

目的分离纯化正常大鼠脾脏2 0S蛋白酶体，并观察其形态特征。

蛋白酶体

1·This paper reviews the biological functions of proteasome in signal transduction and its potential roles in neurodegenerative diseases.

本文综述蛋白酶体在细胞信号转导中的生物学功能和在神经退行性疾病中的可能作用。

2·This review summarizes composition and structure of proteasome, its physiological and pathological actions, and available inhibitors.

本文对蛋白酶体的组成结构、病理生理作用和现有抑制剂进行归纳总结。

3·The proteasome is an abundant multi-enzyme complex that provides the main pathway for degradation of intracellular proteins in eukaryotic cells.

蛋白酶体是真核细胞中含量丰富的多酶复合物，它主要协助降解细胞内的蛋白。

4·The ubiquitin / proteasome system plays an important role in plant growth and development, morphogenesis and disease resistance.

泛素/蛋白酶体系统在植物的生长发育、形态建成和抗病反应等过程中起着重要的作用。

5·Components in charge of this process include ubiquitin, its startup enzymes, and proteasome system.

负责执行这个调控过程的组成成分包括泛素及其启动酶系统和蛋白酶体系统。