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1·CONCLUSION: Morbidity and mortality rates are still high after SPK.

结论：SPK后的并发症和死亡率仍然很高。

2·HGF stimulation could increase the activity of SPK and cellular S1P in ECV304 cells.

肝细胞生长因子(HGF)刺激能增强ECV304细胞SPK的活性和细胞内s1p水平。

3·Objective To observe the effect of Spirulina kinase(SPK) extract on thrombus formation.

结论螺旋藻蛋白激酶提取物具有明显抑制血栓形成的作用。

4·Methods the operation method, therapeutic effect and complications prevention data of 3 cases of SPK were studied.

方法总结了近期施行的3例胰肾联合移植手术的方法、疗效及并发症的防治。

5·Excellent 1 - and 5-year organ survival rates favor the use of SPK in type 1 diabetics associated with end-stage renal disease.

良好的1年和5年移植器官生存率支持采用SPK治疗1型糖尿病相关的终末期肾病。

6·Conclusion This is a practical model with high achievement ratio and rare complications and can be used in further study on SPK.

结论此模型手术成功率高，术后并发症少，可进一步用于SPK的相关研究。

7·Objective To summarize the initial experience of simultaneous pancreas kidney transplantation (SPK) with portal venous and enteric drainage.

目的总结门静脉和肠道引流式胰肾联合移植的初步经验。

8·Sphingosine kinase (SPK) is a key enzyme catalyzing the formation of sphingosine 1 phosphate (S1P), which is a lipid messenger with strong angiogenic activity.

细胞内鞘氨醇激酶（SPK）是催化鞘氨醇生成1-磷酸鞘氨醇（S1P）的限速酶。

9·Conclusion Control of perioperative complications is the focal point of SPK transplantation, and the dosage of immunosuppressive agents must be adjusted individually.

结论胰肾联合移植围手术期并发症的处理是管理的重点，应注意免疫抑制剂的个体化。

10·ABSTRACT: Objective to evaluate the clinical value of color Doppler in monitoring graft flow in patients who underwent simultaneous pancreas-kidney (SPK) transplantation.

摘要：目的探讨彩色多普勒在胰肾联合移植术后移植体血流监测中的应用价值。