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1·He and other biologists studying a wide variety of organisms have found that these particular RNA's direct, in large part, the synthesis of histones, a class of proteins that bind to DNA.

他和其他研究多种生物的生物学家发现，这些特殊的 RNA 在很大程度上直接影响组蛋白的合成，组蛋白是一类与 DNA 结合的蛋白质。

2·Once synthesized, the histones move into the cell nucleus, where a section of DNA wraps around them to form a structure that resembles beads, or knots, on a string.

一旦合成，组蛋白就会进入细胞核，细胞核内的 DNA 片段会将组蛋白包裹起来，形成一种类似串珠或绳结的结构。

3·Histones are basic proteins.

组蛋白是碱性蛋白。

4·The histones are kind of like the spool.

组蛋白就像是线轴。

5·Histones that come together to form the core of the nucleosome.

在一起形成核小体核心的组蛋白。

6·Histones are proteins involved in regulating genes being turned on and off.

组蛋白是涉及到调控基因的蛋白质。

7·Histones are a group of proteins that are associated with chromosomes.

组蛋白是一类结合在染色体上的蛋白质。

8·An octa-mer of histones package DNA into a structure called a nucleosome.

一种组蛋白的八聚物把DNA打包成一种叫做核小体的结构。

9·Histones are the principal structural proteins of eucaryotic chromosomes.

组蛋白是真核细胞染色体中的主要结构蛋白。

10·And the DNA is wrapped around the histones like a few wraps of thread around a spool.

而DNA就像是一些缠绕在线轴上的线一样，缠绕在组蛋白周围。

组蛋白

1·The Molecular Genetics of schizophrenia (MGS) consortium pinpointed an association between schizophrenia and genes in the chromosome-6 region that mediate gene expression, such as histones.

精神分裂症的分子遗传学院会(MGS)精确确定了精神分裂症和6号染色体区域上的基因间的联系，它介导基因表达，比如组蛋白。

2·Where long strands of DNA are tightly coiled around a group of proteins called histones.

其中的DNA长链盘绕紧密围绕一个名为“组蛋白的蛋白质组。”

3·Histones are proteins involved in regulating genes being turned on and off.

组蛋白是涉及到调控基因的蛋白质。

4·Histones organize the DNA and keep it from getting tangled, much like thread wrapped around a spool.

组蛋白组织DNA并防止它杂乱，很像线缠在线轴上。

5·Past structural studies of methylation were hindered by the extreme difficulty of constructing homogeneous samples of histones bearing methyl groups attached to specific lysine residues.

过去甲基化的结构研究被阻碍的原因是因为很难制备组蛋白特定部位赖氨酸甲基化的均一样品。