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1·Objective To observe the analgesic effect of morphine hydrochloride sustained-release tablets on cancer patients at late stage.

目的 探讨奇曼丁 （曲马多缓释片 ）对晚期癌症中度疼痛的疗效及其副作用。

2·Morphine physical dependence was induced on day 10 in SD rats by daily administration of morphine sulphate(MS), but not morphine hydrochloride(MH), in their drinking water.

在饮水中溶入硫酸吗啡，逐日提高吗啡浓度，SD大鼠在饮入吗啡后第10天产生明显的吗啡依赖。 而同样方法饮入盐酸吗啡效果较差。