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1·The police have launched a major operation against drug suppliers.

警方发动了一次打击毒贩的大规模行动。《牛津词典》

2·He is having a major operation.

他正在接受一次大的手术。

3·Weight-loss surgery is a major operation.

这是大手术。

4·She had a major operation last month.

她上个月初了次大手术。

5·Her father underwent a major operation last week.

她父亲上周动了一次大手术。

6·Her mother was about to undergo a major operation.

她的母亲即将经受一次大手术。

7·Her mother was about to undergo a major operation.

她母亲将要经受一次大手术。

8·It take a major operation to extract money from a minor poet.

要从小诗人那儿榨出钱来，得施行一次大手术。

9·It takes a major operation to extract money from a minor poet.

要从小诗人那儿榨出钱来，得施行一次大手术。

10·He must have a major operation on his knee to mend severed ligaments.

他必须在膝盖上动一次大手术，以修复断裂的韧带。