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1·Objective To investigate the relationship of HBV Lumivudine resistant and HBV genotypes and basic core promoter (BCP) mutation.

目的了解拉米夫定耐药与HBV基因型及HBV基本核心启动子(BCP)突变之间的关系。

2·The invention also discloses a new promoter core sequence regulated by DNA methylation.

本发明还公开了新的受到DNA甲基化调控的启动子核心序列。